YOUNG SMALL EXTRACELLULAR VESICLES REJUVENATE REPLICATIVE SENESCENCE BY REMODELING DRP1 TRANSLOCATION-MEDIATED MITOCHONDRIAL DYNAMICS

Young small extracellular vesicles rejuvenate replicative senescence by remodeling Drp1 translocation-mediated mitochondrial dynamics

Abstract Background Human mesenchymal stem cells have attracted interest in regenerative medicine and are being tested in many clinical trials.In vitro expansion is necessary to provide clinical-grade quantities of mesenchymal stem cells; however, it has been reported to cause replicative senescence and undefined dysfunction in mesenchymal stem cel

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Comparison of the Efficacy and Safety of Rivaroxaban Versus Warfarin in Patients with or Susceptible to Thromboembolic Events

Background: The similar efficacy of rivaroxaban and warfarin in thromboembolic events was recognized in clinical trials.But there are a few studies about the comparison of these medications in real world.This study was designed with the aim of comparing the efficacy and safety of the rivaroxaban and warfarin.Materials and Methods: All patients who

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